Senior Scientist - Retinal and Vascular Biology

Job Description

Our company's Research Laboratories in South San Francisco is a new innovation hub designed to foster partnership between scientists to discover new medicines to improve human health. Retinal and Vascular Biology group, a part of Cardiometabolic Disease Department, is seeking a self-driven and creative Senior Scientist with extensive experience in in vitro and in vivo pharmacology in industry setting. This is an exciting opportunity for an independent bench scientist to drive assay development and optimization to support drug development, target identification and validation activities in close partnership with colleagues in the group, department, Research and Development Division South San Francisco and across broader company network.

The ideal candidate will be an accomplished scientist with minimum of 5-7 years industry experience with demonstrated proficiency in in vitro and in vivo assay development and optimization in retinal and/or vascular diseases. This position requires high level of motivation and dedication to lab experimentation with excellent comprehension of molecular biology, cell signaling pathways, retinal and vascular biology.

Education Minimum Requirement

• BS or MS degree in cell biology, molecular biology, neuroscience, or related biological discipline with minimum 8-10 (BS) or 5-7 (MS) years respectively of relevant professional laboratory research experience.

Specific Responsibilities:

• Employ innovative molecular and cell biology platforms to advance target validation and drug discovery efforts

• Collaborate with multiple stakeholders directly contributing to drug discovery efforts to address high unmet medical need in retinal and vascular disease.

• In vitro and in vivo assay development and optimization in retinal and/or vascular diseases.

• Drive assay development and optimization to support drug development, target identification and validation activities in close collaboration with colleagues in the group, department, Research and Development Division South San Francisco and across broader company network.

Required skills:

• Hands on experience with building in vitro biochemical and cell-based assays utilizing state-of-art technologies

• Technical expertise and experience in pre-clinical ophthalmology in vivo techniques including FA, OCT, ERG and ocular injections

• Ability to independently design, conduct, troubleshoot, and analyze experimental data for target identification and validation purpose

• Demonstrated ability to learn, understand and independently implement new techniques or platforms

• Commitment to experimental excellence and scientific rigor

• Proficiency in using professional data analysis and visualization software such as Spotfire, Excel and GraphPad Prism

• Excellent oral and written communication and presentation skills

• Strong motivation and passion for science

• Strong technical proficiency in assay development

• High level of organizational skills to support multiple projects in matrix environment

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