People Business Partners Lead

GeneDx (Nasdaq: WGS) delivers personalized and actionable health insights to inform diagnosis, direct treatment, and improve drug discovery. The company is uniquely positioned to accelerate the use of genomic and large-scale clinical information to enable precision medicine as the standard of care. GeneDx is at the forefront of transforming healthcare through its industry-leading exome and genome testing and interpretation services, fueled by the world’s largest, rare disease data sets. For more information, please visit www.genedx.com.

Job Summary:
The Lead, People Business Partner is a key leadership role within our People Team, reporting to the Sr. Director of People Experience and working closely with the Head of People and our Management Team. This individual will be responsible for driving our people strategy while directly supporting a business function as a People Business Partner (PBP). They will mentor and lead a team of PBPs, embedding people experience tools and training into the fabric of our organization. With a strong focus on data discovery, insights, and transformation, this leader will use surveys, systems, and feedback mechanisms to tell a compelling story, influence decision-making, and drive meaningful change in a fast-evolving environment.

The PBP team serves as the main point of contact for all people matters, including compensation and benefits liaison, employment law and relations, performance frameworks, change management, and people best practices. This leader will ensure that the PBP team is aligned, well-equipped, and positioned as trusted advisors to employees and leaders.

This role is ideal for a bold, strategic, and people-first leader who thrives in a transformational environment and is passionate about making an impact through data-driven insights, leadership coaching, and innovative people strategies.

Primary Responsibilities:

 Lead & Mentor the PBP Team:

• Provide coaching, development, and guidance to the PBP team, ensuring alignment with business needs and people strategies.
• Embed people experience tools, training, and best practices into everyday business operations.
• Ensure PBPs are trusted advisors for all people-related matters, including compensation and benefits inquiries, employee relations, performance frameworks, and employment law compliance.
• Foster a culture of continuous learning, accountability, and high performance.

Be a Strategic Business Partner:

• Act as the direct PBP for a designated function, demonstrating best-in-class support and engagement strategies.
• Build strong relationships with management and the Executive Leadership Team (ELT) to deeply understand business needs and challenges.
• Use people data, engagement surveys, and feedback to craft insights and drive strategic initiatives that enhance employee experience and organizational effectiveness.
• Provide guidance on change management, talent strategies, and people best practices to support leaders in driving business success.

Drive Change & Continuous Improvement:

• Lead change management efforts that support our evolving business, ensuring alignment between where we are today and where we need to be.
• Identify opportunities to improve processes, leverage technology, and implement scalable solutions that empower leaders and employees.
• Champion transformation initiatives that create ease, efficiency, and impact across the organization.

Leverage Data to Drive Decisions:

• Conduct deep analysis of people data to uncover trends, measure effectiveness, and provide strategic recommendations.
• Develop and present data-driven insights that inform leadership decisions and drive meaningful change.
• Ensure that people metrics are aligned with business goals and talent strategies.

Foster an Agile & Forward-Thinking Culture:

• Exhibit flexibility, curiosity, drive, and accountability in navigating the complexities of a growing, dynamic organization.
• Serve as a thought partner to leaders, helping them anticipate and adapt to evolving workforce needs.
• Proactively identify challenges and opportunities, ensuring the People Team is seen as a strategic driver of business success.

Experience & Qualifications:

• 8+ years of experience in HR, including at least 3 years in a people leadership role.
• Proven ability to manage and develop high-performing teams.
• Experience as a strategic PBP, partnering with senior leaders/executive leadership in a complex, fast-paced environment.
• Strong analytical skills with the ability to interpret data and use insights to drive decisions.
• Deep expertise in change management, organizational design, and leadership development.
• Exceptional communication and relationship-building skills, with the ability to influence and drive impact with a high level of HR knowledge and expertise when working with stakeholders. You will be accountable for driving decision-making, so clarity of thought is essential.
• Strong presentation skills; comfortable in front of Senior leadership and decision makers.
• Exceptional understanding of the HR space, including performance management, leadership development, organizational design development, talent management, compensation, employee law and relations, and most importantly diversity, equity, and inclusion methodologies.
• Results-focused and deadline-driven, with a strong ability to think outside the box, challenge norms and traditional ways of working, and synthesize lots of complex information to come up with solutions that align with who we are.
• Ability to navigate ambiguity, lead through transformation, and drive continuous improvement.
• Comfort working in an ambiguous remote work environment with little oversight. You use a high degree of judgment to determine what needs to be done well and what needs to be done now, while juggling an extensive range of priorities.
• Ability to balance working individually and autonomously whilst also working in and alongside a range of teams — you are comfortable being part of a team, leading projects, or owning things; whatever the job calls for.
• Proficient in MS Office Suite, with emphasis on Excel and experience running and analyzing reports.
• Ability to travel 10% of the time  

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Science - Minded, Patient - Focused. 

At GeneDx, we create, follow, and are informed by cutting-edge science. With over 20 years of expertise in diagnosing rare disorders and diseases, and pioneering work in the identification of new disease-causing genes, our commitment to genetic disease detection, discovery, and diagnosis is based on sound science and is focused on enhancing patient care.

Experts in what matters most. 

With hundreds of genetic counselors, MD/PhD scientists, and clinical and molecular genomics specialists on staff, we are the industry’s genetic testing experts and proud of it. We share the same goal as healthcare providers, patients, and families: to provide clear, accurate, and meaningful answers we all can trust.

SEQUENCING HAS THE POWER TO SOLVE DIAGNOSTIC CHALLENGES.

From sequencing to reporting and beyond, our technical and clinical experts are providing guidance every step of the way:

TECHNICAL EXPERTISE

• High-quality testing: Our laboratory is CLIA certified and CAP accredited and most of our tests are also New York State approved.
• Advanced detection: By interrogating genes for complex variants, we can identify the underlying causes of conditions that may otherwise be missed.

CLINICAL EXPERTISE

• Thorough analysis: We classify variants according to our custom adaptation of the most recent guidelines. We then leverage our rich internal database for additional interpretation evidence.
• Customized care: Our experts review all test results and write reports in a clear, concise, and personalized way. We also include information for research studies in specific clinical situations.
• Impactful discovery: Our researchers continue working to find answers even after testing is complete. Through both internal research efforts and global collaborations, we have identified and published hundreds of new disease-gene relationships and developed novel tools for genomic data analysis. These efforts ultimately deliver more diagnostic findings to individuals.

Learn more About Us here.

Our Culture

At GeneDx, we are dedicated to cultivating an environment where creativity and innovation thrive. We believe in the power of community and collaboration, where diverse perspectives are embraced, and every voice contributes to our shared success. Our team is a vibrant mix of professionals who challenge and support each other in equal measure, fostering growth both personally and professionally. When you join us, you're not just taking on a job—you're joining a movement. A movement that champions curiosity, embraces change, and believes in making an impact, one patient at a time. Cultural principles we live by:  

• Be bold in our vision & brave in our execution. 
• Communicate directly, with empathy. 
• Do what we say we're going to do.  
• Be adaptable to change.  
• Operate with a bias for action.    

Benefits include:

• Paid Time Off (PTO)
• Health, Dental, Vision and Life insurance
• 401k Retirement Savings Plan
• Employee Discounts
• Voluntary benefits

GeneDx is an Equal Opportunity Employer.

All privacy policy information can be found here.