Senior Principal Scientist, Chemical Biotechnologies

USA - New Jersey - Rahway

Job Description


The Senior Principal Scientist reports to the Senior Director Chemical Biotechnologies of Process Research & Development Enabling Technologies, our Company's Research Laboratories. As a scientific leader within Chemical Biotechnologies (CBT), they are responsible for delivering technical innovation, both personally and through mentorship of others, and in driving the scientific strategy of the CBT group. The Senior Principal Scientist manages and prioritizes a portfolio of work that includes direct project support of the current our Company's clinical pipeline and prospective technology development that enhances our ability to deliver on the pipeline of the future. This includes technical oversight of laboratory-based process development and characterization, scale-up and activities to support technology transfer and regulatory filings.

The CBT group is an interdisciplinary team responsible for the discovery, development, and application of proteins and other biomolecules to support our Company's Pipeline from Discovery to Commercial launch across small molecules, biologics, and vaccines. The Senior Principal Scientist cultivates and drives scientific excellence and innovation by contributing their expertise and experience to drive invention and implementation of new biomolecule applications. As a scientific leader with deep subject matter expertise in chemistry, biocatalysis and protein engineering, they will be expected to impact the scientific strategy and portfolio broadly, including via their own lab experimentation and their guidance of fellow scientists both in and out of the lab. They will also use their network and knowledge of emerging biotechnology advances to drive these contributions.

Critical tasks include: (1) developing innovative enzymatic solutions to complex chemistry problems across a diverse portfolio of projects from the preclinical to commercial synthesis phase, (2) advancing novel capabilities to design, generate, and test libraries of engineered proteins with world-class efficiency, (3) mentoring, coaching, and training scientists both in and out of the lab to drive technical excellence, and (4) proactively identifying and capitalizing on impactful new opportunities and applications of biomolecules across modalities. These tasks will enable the incorporation of improvements to existing workflows and invention of new ones that fundamentally shift our ability to deliver on the pipeline of the future.

A successful candidate is expected to collaborate with their peers on developing strategies and priorities for biomolecular applications. They are responsible for working closely with their counterparts across Development Sciences and Clinical Supply (DSCS), Discovery, Preclinical and Translational Medicine (DPTM), and our Company's Manufacturing Division, to deliver on their critical tasks.

Through their scientific leadership, strategic input, and …

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