Scientist, In Vivo Antibody Discovery, Molecular Discovery

Job Description

We are seeking a talented Scientist to join our Antibody Generation group located in South San Francisco, CA. The Scientist will be a part of a diverse team that is focused in the areas of in vivo antibody discovery, high throughput screening, and antibody sequencing to help isolate novel reagent and therapeutic antibodies. They will work closely with other team members and groups throughout the organization to help execute and troubleshoot antibody discovery programs. Additionally, they will work to improve platform antibody discovery processes to help meet rapid project timelines.

What you will do:

• Design and execute antibody discovery campaigns using a diverse set of in vivo antibody discovery platforms and animal species:

  • Including antigen selection, animal immunization, hybridoma or B-cell screening, assay development, antibody sequencing, and antibody characterization.

  • Analyze and interpret experimental data, prepare clear and concise reports to communicate results to project teams.

  • Maintain detailed laboratory records, ensuring compliance with established protocols, quality control measures, and regulatory guidelines.

• Stay updated with external advancements and scientific literature in the field of antibody discovery and characterization.

• Promote the external reputation of our company’s Discovery Biologics team.

What you will need to be successful in this role:

Qualifications & Experience:

• Bachelor’s (with 2+ years postgrad experience) or Master’s degree in biochemistry, cell biology, molecular biology or related biological discipline and relevant professional laboratory research experience listed below.

• Experience in in vivo antibody discovery approaches supporting therapeutic programs.

• Excellent communication and collaboration skills.

• Ability to manage multiple projects simultaneously.

Required skills:

• Hands-on experience in one or more antibody discovery platforms using immunized B-cell repertoires (i.e., Hybridoma fusion or B-cell culture, and/or microfluidic approaches, and Next Generation Sequencing).

• Hands-on laboratory skills in cell culture, molecular biology, high-throughput screening (by ELISA or Flow Cytometry), assay development, and NGS.

• Champion for a diverse and inclusive culture.

Preferred skills:

• Experience conducting high-throughput screens for binding or function using various assay formats (ELISA, FACS, Meso Scale Discovery etc.).

#EligibleforERP

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace.  All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics.  For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

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U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.

The Company is required to provide a reasonable estimate of the salary range for this job in certain states and cities within the United States. Final determinations with respect to salary will take into account a number of factors, which may include, but not be limited to the primary work location and the chosen candidate’s relevant skills, experience, and education.

Expected US salary range:

Available benefits include bonus eligibility, long term incentive if applicable, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days. A summary of benefits is listed here.

San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

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Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.  No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. 

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