Scientist- Biologics Process Research & Development

Job Description

Our Research Scientists are our Inventors.  Using innovative thinking, state-of-the-art facilities, and robust scientific methodology, we partner to deliver the next medical breakthrough.

Biologics Process Research & Development (BPR&D) within our company'sResearch Laboratories is on a mission to rapidly deliver diverse biotherapeutics to patients by efficiently developing innovative, robust manufacturing processes and technologies. To achieve this, we work closely with colleagues in Discovery, Pre-clinical, Early Development, Analytical, Formulation, and Commercial Manufacturing while providing a diverse and inclusive environment for all. Beyond process development for pipeline biologics, we innovate and build next generation biomanufacturing technologies. Examples include investments for development of continuous manufacturing, green and sustainable processes, and proprietary technology platforms. We actively publish and engage with the scientific community to influence the field.

BPR&D includes three lab-facing technical functional areas: Process Cell Sciences (PCS), Upstream and Downstream Process Development & Engineering. The latter two together form our Biologics’ Process Development (BPD) group. This job posting covers opportunities for the BPD group.  We are actively looking for highly motivated people with a passion for innovation and interest in contributing to upstream and/or downstream bioprocessing.

As a Scientist in BPR&D, you will work with immensely creative and collaborative team members to design and develop robust processes in support of early- and late-stage biologics. You will innovate to support our company's biologics pipeline and production platforms through rigorous scientific principles. You will have the opportunity to apply and integrate innovation into biologic process sciences to establish our company as the industry leader in next-generation biologics manufacturing.  You may also be expected to contribute to additional areas of interest such as biophysical, reactor, process, economic and/or multivariate modeling as we are committed to leveraging digital ways of working to enhance our ability to design robust processes.

Responsibilities include but are not limited to:

• Develop innovative and disruptive technologies for next-generation biologics manufacturing processes

• Develop and characterize robust clinical processes capable of delivering multi-kilogram quantities of therapeutics

• Design and conduct experiments related to cell-line development, upstream or downstream bioprocessing

• Integrate unit operations with relevant process control and monitoring platforms

• Collaborate across BPR&D, process analytics, and other functional areas in research and manufacturing to advance the biologics pipeline

• Conduct laboratory- and/or pilot-scale studies to support scale-up and technology transfer to manufacturing sites

• Contribute to a safe and compliant laboratory work environment

MINIMUM EDUCATION REQUIREMENTS:

Education:

BS with 2+ years OR MS degree (expected graduation by May 2025) in Chemical/Biochemical/Biomedical Engineering, Biotechnology, Biochemistry, Molecular Biology, or related fields with relevant bioprocess experience and research background in molecular biology, cell culture or protein purification

REQUIRED EXPERIENCE AND SKILLS:

• Experience with one or more of molecular biology, protein expression, mammalian cell culture, protein purification, biochemical engineering, or analytical technologies

• Scientific understanding of the engineering principles behind recombinant protein production and purification

• Ability to comprehend and execute experiments independently

• Ability to organize, communicate, analyze, and present experimental data to drive conclusions and further study designs

• Knowledge of aseptic technique, protein biophysical properties, and general protein laboratory practices 

• Demonstrated ability to independently prepare technical documents and scientific presentations to capture development progress, scientific investigations, and technology development output

• Basic understanding of statistical methods and data analysis tools

• Strong passion and commitment to integrate science and innovation into biologic process development

• Ability to excel in a collaborative and matrix environment

PREFERRED EXPERIENCE AND SKILLS:

• Demonstrated capabilities in understanding and operating bioanalytical techniques to characterize microbial or cell culture processes

• Ability to think critically with excellent problem solving and troubleshooting skills

• High throughput screening, automated bioreactor systems, and liquid handlers

• Experience with process transfer to clinical or commercial manufacturing facilities

• Knowledge of process control and workflow automation tools

• Strong foundation in statistical analysis, design of experiments, data science, computational modeling

#BPRD #PRD #EligibleforERP #EBRG #vetjob

NOTICE FOR INTERNAL APPLICANTS

In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace.  All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics.  For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement​

Pay Transparency Nondiscrimination

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.

The Company is required to provide a reasonable estimate of the salary range for this job in certain states and cities within the United States. Final determinations with respect to salary will take into account a number of factors, which may include, but not be limited to the primary work location and the chosen candidate’s relevant skills, experience, and education.

Expected US salary range:

Available benefits include bonus eligibility, long term incentive if applicable, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days. A summary of benefits is listed here.

San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully 
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.  No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. 

Employee Status:

Relocation:

VISA Sponsorship:

Travel Requirements:

Flexible Work Arrangements:

Shift:

Valid Driving License:

Hazardous Material(s):

Job Posting End Date:

*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.