Principal Scientist, Analytical R&D

Job Description

The Principal Scientist-Team Lead is responsible for providing direct technical leadership and management for a team of scientists (3-5) that are embedded with the chemical biotechnologies group within the Process Research and Development, Enabling Technologies Organization. The team provides analytical expertise that ranges from high throughput chromatography and mass spectrometry and advanced bioanalytical assays to support enzyme discovery, evolution, and manufacturing efforts.

The Principal Scientist will report to the Data Rich Measurements (DRM) Lead and will be accountable for delivering analytical methodologies and platforms that may accelerate the pace of the discovery, evolution, and manufacturing of enzymes to enable the biocatalysis strategy of our Company’s Process Research and Development organization. Additionally, the role will represent the function at internal governance and CMC teams within the new product development and commercialization (NPDC) framework. The role will be accountable for partnering with the DRM lead in the areas of scientific strategy, proactive resource planning and allocation to maximize impact and talent development of scientists under his/her direct supervision.

Maintaining a strong external network across the academic community is expected, as well as advancing an internal culture of scientific excellence and collaboration.  As a member of our team, you will be joining scientific problem solvers who are dedicated to creating the life-changing medicines of tomorrow.

Education Minimum Requirements: 

• Ph.D. in Chemistry/Biochemistry/Chemical Biology or related field with 7-10 years of relevant industry experience OR

• MS degree with 10+ years of relevant industry experience

Required Experience and Skills: 

• Direct people management or scientific supervisory experience

• Formal training and or hands on experience in high-throughput analytical and bioanalytical methodologies including various forms of chromatographic techniques (HIC, IEX, SEC) and hyphenated techniques including (LC-MS/MS, LC-CAD/ELSD, SEC-MALS), SDS-PAGE, CE-SDS and other affinity-based platforms.

• A track record of scientific excellence demonstrated by publications in peer reviewed journals and presentations at scientific conferences.

• Excellent verbal and written communication skills, creativity, and strong interpersonal skills.

• Ability to deliver complex objectives under challenging timelines in a rapidly changing environment.

• Ability to work in a matrix team environment with cross-functional interactions.

Preferred Experience and Skills:

• Experience working within CMC frameworks within the bio-pharmaceutical industry.

• Ability to set and drive scientific strategy.

• Foundational experience in enzymology and protein engineering.

#AR&D

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U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.

The Company is required to provide a reasonable estimate of the salary range for this job in certain states and cities within the United States. Final determinations with respect to salary will take into account a number of factors, which may include, but not be limited to the primary work location and the chosen candidate’s relevant skills, experience, and education.

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Available benefits include bonus eligibility, long term incentive if applicable, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days. A summary of benefits is listed here.

San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

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Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.  No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. 

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