Medical Director, Rheumatology

Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients. 

We are seeking an experienced medical professional to serve as a Medical Director, Rheumatology, reporting to the Vice President of Clinical Development, Rheumatology. The successful individual will play a pivotal role in advancing our clinical programs from Phase 2 through regulatory approval. You will contribute to the strategic planning, execution, and management of the SLE program which currently consists of a Phase 2b study (the LUMUS Trial) designed to be the first of two pivotal studies with ESK-001 in SLE. ESK-001 is a highly selective TYK-2 inhibitor which has the potential to be a best-in-class oral treatment for SLE.

Collaborating closely with cross-functional teams, this person will contribute to the scientific and medical vision, and provide leadership in the development of innovative therapies to address unmet medical needs in SLE and related inflammatory conditions.

RESPONSIBILITIES:

· Serve as the Sponsor medical monitor for the LUMUS trial and collaborate with CRO to provide monitoring oversight;

· Review and follow all SAEs;

· Participate in in-stream data reviews;

· Interact with PIs and site staff (e.g.: by raising and responding to queries);

· Draft key study documents (e.g.: responses to Regulatory requests for information);

· Work on the cross-functional Study Execution Team for LUMUS and broadly across Rheumatology Clinical Development programs at Alumis;

· Contribute to the design and development of clinical studies as well as other cross-functional initiatives;

· Has opportunities for external engagement (e.g.: participation in Investigator Meetings, external Data Monitoring Committee reviews, etc…);

· Maintains the highest levels of integrity and ethical standards for scientific inquiry in drug development.

QUALIFICATIONS AND SKILLS REQUIRED:

· Licensed physician (required);

· Board certification in rheumatology or related field (desired);

· Industry experience in pharmacovigilance or clinical development (helpful);

· Ability to interact effectively in a cross-functional setting;

· Strong interpersonal and communications skills (written and verbal) to effectively address all levels within an organization;

· Ability to assess, understand, and communicate continuously expanding medical and scientific information;

· Ability to work across diverse teams in a matrixed organizational structure, both as a leader and as part of a cross-functional team;

· Approaches deliverables in an organized manner with attention to detail and is able to meet timelines in a fast-paced environment;

· Able to work productively with a high level of independence.

The salary range for this position is $285,000 USD to $325,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices.

This position is located in South San Francisco, CA and employees are expected to be onsite Tuesday-Thursday. Open to remote applicants with requirement to be onsite once a month.

Alumis Inc. is an equal opportunity employer.

Alumis compensation packages include generous stock option grants for all employees as well as an annual bonus program.  

Other benefits include:

• Health insurance premiums paid at 90% for employee, 80% for dependents
• Free access to Genentech Bus & Ferry Share program
• $100 monthly cell phone stipend
• Unlimited PTO for Exempt employees
• Free onsite gym and a kitchen stocked with yummy snacks and drinks!

We are a hard-working, collaborative team on a mission to transform patient’s lives-- and we aspire to elevate, challenge and nurture one another along the way.