Director, Strategic Program Execution

Career Category

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Director, Strategic Program Execution

What you will do

Let’s do this. Let’s change the world! The Contracts and Pricing Execution (CPE) team is responsible for managing the execution of US Commercial Discount payment processes and Government Programs, ensuring compliance and operational excellence in these critical areas. With several transformative projects impacting CPE—including IRA implementation, system upgrades (Model N and SAP), and Gross-to-Net automation transformation initiatives—the need for a strategic leader to provide organizational oversight has never been greater.

The Director, Strategic Program Execution will be a key leader within the CPE team, reporting directly to the CPE Executive Director. This role is tasked with providing strategic and organizational oversight, ensuring alignment across multiple critical projects and initiatives. The Director will focus on delivering impactful results that support strategic priorities and advance organizational objectives. Additionally, this individual will lead the Center of Excellence (CoE) team, which is dedicated to ensuring that CPE business systems operate effectively while driving optimization opportunities.

Key Responsibilities:

• Strategic and Organizational Program Leadership: Provide strategic and organizational oversight across major CPE initiatives, including IRA implementation, system upgrades (Model N and SAP), and Gross-to-Net Transformation efforts.

• Leadership Engagement: Ensure leadership remains informed and aligned with the strategic direction of CPE initiatives by serving as a key advisor. This role will involve delivering clear updates, actionable insights, and strategic recommendations on program progress, priorities, risks, and opportunities.

• Cross-Functional Alignment: Collaborate with teams across Finance, Policy, Contracts and Pricing, USV&A Insights, Audit, Legal, and …