Associate Principal Scientist, NMR / Analytical R&D

Job Description

Our Scientists are our Inventors. We deliver robust scientific data and interpretation that drives the commercialization of breakthrough therapeutics using innovative thinking, state-of-the-art facilities and modern equipment. Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity and teamwork of people like you. To this end, we strive to create an environment of mutual respect, encouragement and teamwork. As part of our global team, you’ll have the opportunity to collaborate with talented and dedicated colleagues while developing your career.

The Analytical Research and Development organization in South San Francisco, CA is seeking a motivated Associate Principal Scientist with technical expertise in solution state NMR for a role that primarily involves structure elucidation and investigation of small molecule drugs, peptides, and biologics. The successful candidate is expected to collaboratively work with synthetic, computational and analytical scientists, understand their problem statements, and collaboratively design and provide solutions, establish new NMR methods, and drive strategic innovation in the field of NMR. The candidate should be able to work proactively and independently and influence decisions and solutions spanning a wide diversity of problem statements across our Company Research Laboratories. The role will require the candidate to network across a range of departments and effectively collaborate with stakeholders. The role will additionally require a strong ability to mentor scientists on the NMR team and exemplify positive ways of working which support diversity, inclusion, and a positive culture.

The ideal candidate is expected to be helping drive the field of NMR. This candidate will have an established track record of advancing scientific excellence through external presentations and publications. The role will involve mentorship of NMR colleagues. Additionally, the candidate will have advanced knowledge of analytical experimental design and the ability to provide technical leadership across all major pipeline modalities including small molecules, peptides, antibodies, proteins, ADCs, and vaccines. Finally, this Associate Principal Scientist will be a partner in problem solving providing key leadership and driving collaboration both internally and externally.

Primary job responsibilities:

• Work performed in the NMR group includes structure elucidation, mechanism elucidation, reaction elucidation, analytical method development, physicochemical characterization, and quantitative NMR analysis
• Provide support for discovery research, discovery process chemistry, and analytical development, formulation, identification of process impurities, drug substance and product degradants, and characterization of other unknown molecules
• Meet with department members across functional teams to understand their scientific challenges. Propose and develop collaborative solutions with the NMR …