Associate Principal Scientist, Biologics Process Development

Job Description

Our Research Scientists are our Inventors. Using innovative thinking, state-of-the-art facilities, and robust scientific methodology, we partner to deliver the next medical breakthrough.

BPR&D within Our Research Laboratories is on a mission to rapidly deliver diverse biotherapeutics to patients by efficiently developing innovative, robust manufacturing processes and technologies. To achieve this, we work closely with colleagues in Discovery, Pre-clinical, Early Development, Analytical, Formulation, and Commercial Manufacturing while providing a diverse and inclusive environment for all. Beyond process development for pipeline biologics, we innovate and build next generation biomanufacturing technologies. Examples include investments for development of continuous manufacturing, green and sustainable processes, and proprietary technology platforms. We actively publish and engage with the scientific community to influence the field.

We are seeking a highly motivated and energetic individual to join our Biologics Process Development Department as Associate Principal Scientist. In this role, the successful candidate will work closely with highly motivated team of Scientists and Engineers in the Upstream Process Development area and contribute to CMC development of our company's pipeline, playing an active role in design, development and optimization of cell culture processes and transfer processes to clinical and commercial manufacturing sites. You will also participate in developing and refining strategies related to next generation processes through technology development initiatives for assets in early and late-stage clinical development. 

Responsibilities include, but not limited to:

• Participate in and/or lead upstream development of first-in-human and commercial processes by efficiently developing high yield, robust and scalable cell culture processes.

• Responsible for process characterization and regulatory filing activities to ensure a smooth and clear path to successful commercialization.

• Collaborate with downstream process development, Analytical R&D, and other cross-functional teams in both Research and Manufacturing to advance biologics pipeline

• Advance and improve upstream platform processes through creative initiatives that increase operational efficiency and reduce costs.

• Assess new technologies, and industry strategies that are relevant to our company

• Collaborate with academia, industry partners, and vendors to drive development, innovation, and adoption of new technologies.

• Keep up to date with the external patents and literature; actively present and publish externally and pursue patenting strategies.

• Mentor junior scientists.

MINIMUM EDUCATION REQUIREMENTS: 

• Ph.D. with 3+ years OR Master’s with 6+ years OR B.S. with 8+ years of industry experience and background in chemical engineering, Bioengineering, Biological Engineering, or a related field

REQUIRED EXPERIENCE AND SKILLS:

• Technical background and hands-on experience with mammalian cell culture and fed-batch processes …